Description

Angiogenin, Methionyl-(-1)- is a recombinant protein variant of the angiogenic ribonuclease, angiogenin. This compound is of significant interest for its role in stimulating the formation of new blood vessels, a critical process in both physiological and pathological contexts. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science research sectors for studying angiogenesis, cancer biology, and developing novel therapeutic agents.

Application

• Biomedical Research: Fundamental studies on angiogenesis, endothelial cell proliferation, and tumor biology.
• Drug Discovery & Development: Target validation and screening for anti-angiogenic cancer therapies or pro-angiogenic wound healing treatments.
• Cell Culture & Assay Development: Used as a critical growth factor component in specialized cell culture media and in vitro assay systems.
• Biochemical Reagent: Serves as a high-purity standard or active ingredient in enzymatic and protein interaction studies.
• Therapeutic Protein Research: Investigation into protein engineering, stability, and delivery mechanisms for peptide-based pharmaceuticals.

Basic Information

Product Name	Angiogenin, Methionyl-(-1)-
CAS No.	120298-94-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Methionyl Angiogenin; Met-(-1)-Angiogenin; ANG (Met-(-1)); Angiogenin Precursor; RNASE5 Variant; Ribonuclease 5 (Met-(-1)); Tumor Angiogenesis Factor; Recombinant Human Angiogenin (Met-(-1))
EINECS	Contact for details

Quality Control

Our Angiogenin, Methionyl-(-1)- is produced and tested under stringent quality systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity (by HPLC), endotoxin levels, and biological potency are provided to support research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Biological Activity	Determined by cell-based assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.