Description

(S)-(-)-Mosapramine is a high-purity, single-enantiomer compound of significant interest in advanced pharmaceutical research and development. This chiral molecule serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly in the central nervous system (CNS) domain. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors requiring precise stereochemical control for drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and psychiatric disorders.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical laboratories to ensure product purity and regulatory compliance.
• Biochemical Research: Employed in preclinical studies to investigate receptor binding affinity, metabolic pathways, and the pharmacological profile of stereospecific compounds.
• Process Chemistry: Serves as a starting material or intermediate in optimizing asymmetric synthesis routes for scale-up and commercial manufacturing.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and studies on the structure-activity relationships (SAR) of chiral molecules.

Basic Information

Product Name	(S)-(-)-Mosapramine
CAS No.	120167-35-3
Molecular Formula	C₂₄H₃₀ClN₃O₂
Molecular Weight	428.0 g/mol
Synonyms	(S)-Mosapramine; (-)-Mosapramine; (S)-(-)-Mosapramine Citrate; Mosapramine (S-enantiomer); (3S)-3-[4-(4-chlorophenyl)-1-piperazinyl]-8,8-dimethyl-6,7,8,9-tetrahydro-3H-pyrido[2,1-b][1,3]benzoxazin-1-one; Y-516; Cremin
EINECS	Contact for details

Quality Control

Our (S)-(-)-Mosapramine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.