Description

Carbamic Acid, (3-Chloro-1-Oxopropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic intermediate of significant interest in advanced synthetic chemistry. This compound matters for its role as a key building block in the synthesis of complex molecules, offering a protected amine functionality and a reactive carbonyl group. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds. Its precise structure enables controlled chemical transformations essential for modern drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected amino acid or peptide-like backbone.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its chloro and ester groups provide sites for further functionalization.
• Peptidomimetic Research: Serves as a scaffold in medicinal chemistry for creating peptide mimics to improve metabolic stability and bioavailability of drug candidates.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex heterocycles and other advanced organic molecules.
• Protecting Group Chemistry: The tert-butyl ester group can act as a protecting group for carboxylic acids in multi-step synthetic sequences.

Basic Information

Product Name	Carbamic Acid, (3-Chloro-1-Oxopropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	120158-04-5
Molecular Formula	C8H14ClNO3
Molecular Weight	207.65 g/mol
Synonyms	1,1-Dimethylethyl (3-chloro-1-oxopropyl)carbamate; tert-Butyl (3-chloropropanoyl)carbamate; N-(tert-Butoxycarbonyl)-3-chloropropionamide; 3-Chloro-N-(tert-butoxycarbonyl)propanamide; Boc-3-chloropropionamide; (3-Chloropropionyl)carbamic acid tert-butyl ester; tert-Butyl 3-chloropropionylcarbamate; BOC-β-chloropropionamide
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Chloro-1-Oxopropyl)-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.