Description

tert-Butyl 4-Methoxybenzylcarbamate is a protected amine derivative, specifically a carbamate, widely used as a key synthetic intermediate in organic chemistry. Its primary value lies in its role as a versatile building block for constructing more complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for API synthesis and advanced material creation.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing benzylamine or aniline moieties.
• Peptide Synthesis: Serves as a protecting group for amines during solid-phase and solution-phase peptide synthesis, preventing unwanted side reactions.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides where specific amine functionality is required.
• Organic Synthesis Reagent: Employed in multi-step organic synthesis to introduce the 4-methoxybenzyl (PMB) protected amine group into target molecules.
• Material Science Research: Acts as a monomer or precursor in the development of specialized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes and labeled compounds for biochemical and diagnostic research.

Basic Information

Product Name	tert-Butyl 4-Methoxybenzylcarbamate
CAS No.	120157-94-0
Molecular Formula	C13H19NO3
Molecular Weight	237.29 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-methoxybenzylamine; Boc-4-Methoxybenzylamine; Boc-PMB-NH2; tert-Butyl N-[(4-methoxyphenyl)methyl]carbamate; 4-Methoxybenzylcarbamic Acid tert-Butyl Ester; N-Boc-4-methoxybenzylamine; (4-Methoxybenzyl)carbamic Acid 1,1-Dimethylethyl Ester; PMB-NH-Boc
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Methoxybenzylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.