Description

Oxybutynin-D10 Hydrochloride is a high-purity, deuterium-labeled internal standard essential for precise bioanalytical quantification. This stable isotope-labeled compound is critical for ensuring accuracy and reliability in pharmacokinetic and metabolism studies, where it compensates for matrix effects and instrument variability. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers conducting LC-MS/MS analysis for drug development and regulatory compliance.

Application

• Internal Standard for LC-MS/MS quantification of Oxybutynin and its metabolites in biological matrices (plasma, urine).
• Use in Pharmacokinetic (PK) and Bioequivalence (BE) studies to ensure analytical method accuracy.
• Metabolite profiling and identification in drug metabolism and excretion studies.
• Supporting method development and validation for GLP/GMP-compliant bioanalysis.
• Calibration standard in high-sensitivity mass spectrometry applications.
• Research tool for studying the pharmacodynamics and toxicokinetics of anticholinergic agents.

Basic Information

Item	Details
Product Name	Oxybutynin-D10 Hydrochloride
CAS No.	120092-65-1
Molecular Formula	C22H21D10ClNO3 • HCl
Molecular Weight	408.41 g/mol (for monoisotopic mass)
Synonyms	4-(Diethylamino)but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate-d10 hydrochloride; Ditropan-d10 HCl; Oxybutynin-d10 HCl; Deuterated Oxybutynin Hydrochloride; [2H10]-Oxybutynin Hydrochloride; Oxybutynin (phenyl-d5, cyclohexyl-d5) Hydrochloride; LS-2633-d10
EINECS	Contact for details

Quality Control

Every batch of Oxybutynin-D10 Hydrochloride is manufactured and tested under strict quality systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, isotopic enrichment, and absence of unlabeled compound. Our quality commitment aligns with the standards expected for critical reference materials in regulated bioanalysis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.