Description

Gadoteridol is a non-ionic, macrocyclic gadolinium-based contrast agent. This compound is critical for enhancing the clarity and diagnostic accuracy of magnetic resonance imaging (MRI) scans. It is primarily required by pharmaceutical manufacturers, diagnostic imaging centers, and research institutions developing advanced contrast media. Gadoteridol CAS NO 120066-54-8 offers high thermodynamic and kinetic stability, which is a key advantage in clinical applications.

Application

• As the active pharmaceutical ingredient (API) in non-ionic MRI contrast agents for clinical diagnostics.
• In the formulation of injectable solutions used for central nervous system (CNS) and body imaging.
• For pharmaceutical research and development of next-generation diagnostic imaging products.
• As a reference standard in analytical quality control and regulatory compliance testing.
• In preclinical and clinical studies evaluating the safety and efficacy of gadolinium-based agents.
• For the development of targeted contrast agents in molecular imaging research.

Basic Information

Product Name	Gadoteridol
CAS No.	120066-54-8
Molecular Formula	C17H29GdN4O7
Molecular Weight	558.68 g/mol
Synonyms	Gadoteridol; ProHance; Gadoteridolum; Gd-HP-DO3A; (10-[2-Hydroxypropyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato)gadolinium; Gadolinium-1,4,7-tris(carboxymethyl)-10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane; Gadoteridol USP; Gadolinium chelate HP-DO3A
EINECS	Contact for details

Quality Control

Our Gadoteridol is manufactured and tested to meet stringent pharmaceutical standards. Quality assurance protocols are designed to ensure compliance with relevant pharmacopoeial monographs, including USP. Each batch is supported by a comprehensive Certificate of Analysis (COA) that details purity, assay, impurity profiles, and residual solvent levels, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Free Gadolinium	≤ 0.1%
pH (1% solution)	6.0 - 8.0
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.