Description

n-Boc-L-Homoserine Methyl Ester 4-Methylbenzenesulfonate is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in the preparation of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to incorporate the homoserine moiety into non-peptide structures for drug discovery programs targeting various diseases.
• Protected Amino Acid Derivative: Serves as a Boc-protected, tosylate-activated building block for controlled chain elongation in complex molecule assembly.
• Bioconjugation Chemistry: Employed in the synthesis of linker molecules and modified biomolecules for targeted drug delivery systems.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	n-Boc-L-Homoserine Methyl Ester 4-Methylbenzenesulfonate
CAS No.	120042-09-3
Molecular Formula	C17H25NO7S
Molecular Weight	387.45 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-4-(methyloxy)-4-oxobutyl 4-methylbenzenesulfonate; L-Homoserine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester, 4-methylbenzenesulfonate (1:1); Boc-L-Homoserine-OMe.TosOH; Methyl N-Boc-L-homoserinate 4-methylbenzenesulfonate; tert-Butyloxycarbonyl-L-homoserine methyl ester tosylate; N-Boc-L-homoserine methyl ester p-toluenesulfonate; Boc-Hse-OMe.Tos; Boc-L-Homoserine methyl ester tosylate salt
EINECS	Contact for details

Quality Control

Our n-Boc-L-Homoserine Methyl Ester 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided on COA
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.