Description

2,5-Difluorobenzenesulfonamide is a high-purity fluorinated aromatic sulfonamide building block. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, valued for its ability to modulate biological activity and physicochemical properties. It is primarily sought by research and development teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, where the difluoro substitution pattern enhances bioavailability and target binding.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with unique surface properties or chemical resistance.
• Chemical Research: A versatile reagent in organic synthesis for introducing the sulfonamide pharmacophore and fluorine atoms into complex molecules.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	2,5-Difluorobenzenesulfonamide
CAS No.	120022-63-1
Molecular Formula	C6H5F2NO2S
Molecular Weight	193.17 g/mol
Synonyms	2,5-Difluorobenzenesulfonamide; Benzenesulfonamide, 2,5-difluoro-; 2,5-Difluorophenylsulfonamide; 2,5-Difluorobenzene-1-sulfonamide; 1,4-Difluoro-2-sulfamoylbenzene; 2,5-DFBSA; 2,5-Difluoro-N-sulfonylbenzenamine
EINECS	Contact for details

Quality Control

Our 2,5-Difluorobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.