Description

2,6-Bis(tert-Butoxycarbonylamino)Hexanoic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a stable, orthogonal protecting group strategy for diamino functionalities, enabling precise and complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of peptide-based therapeutics, novel drug candidates, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex peptide drugs, peptidomimetics, and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a diamino acid moiety with Boc-protected amines.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker or spacer molecule for bioconjugation applications, attaching drugs to antibodies or other biomolecules.
• Chemical Biology Research: Employed in the design and synthesis of probes, inhibitors, and other tools for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, protected amino acid architectures.
• Material Science: Potential monomer for creating novel polyamides or specialty polymers with unique properties.

Basic Information

Product Name	2,6-Bis(tert-Butoxycarbonylamino)Hexanoic Acid
CAS No.	119962-72-0
Molecular Formula	C16H30N2O6
Molecular Weight	346.42 g/mol
Synonyms	2,6-Bis[(tert-butoxycarbonyl)amino]hexanoic acid; N2,N6-Bis-Boc-L-lysine; Nα,Nε-Di-Boc-L-lysine; Boc-Lys(Boc)-OH; (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid; N2,N6-Di-tert-butoxycarbonyl-L-lysine; L-Lysine, N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-; Di-Boc-L-lysine
EINECS	Contact for details

Quality Control

Our 2,6-Bis(tert-Butoxycarbonylamino)Hexanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP manufacturing standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.