Description

Fmoc-o-Ethyl-L-Tyrosine CAS NO 119894-20-1 is a protected derivative of the amino acid L-tyrosine, specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly when incorporating modified tyrosine residues. It is an essential building block for the pharmaceutical, biotechnology, and life science research industries, enabling the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Primary use as a protected amino acid building block for the Fmoc/t-Bu strategy.
• Pharmaceutical Intermediate: Key raw material in the research and production of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used to introduce a modified tyrosine moiety with an ethyl-protected phenolic hydroxyl group into proteins or other biomolecules.
• Chemical Biology Research: Essential for synthesizing custom peptides for structure-activity relationship (SAR) studies and probe development.
• Material Science: Potential use in creating peptide-derived polymers or surface coatings with specific functional properties.

Basic Information

Product Name	Fmoc-o-Ethyl-L-Tyrosine
CAS No.	119894-20-1
Molecular Formula	C₂₆H₂₅NO₆
Molecular Weight	447.48 g/mol
Synonyms	Fmoc-Tyr(OEt)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-ethyl-L-tyrosine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-(4-ethoxyphenyl)propanoic acid; Fmoc-O-ethyl-L-tyrosine; Fmoc-L-Tyrosine(O-ethyl); N-Fmoc-O-ethyl-L-tyrosine; Fmoc-Tyr(OEt)-OH (abbreviation); Fmoc-L-Tyr(OEt)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-o-Ethyl-L-Tyrosine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	-10.0° to -14.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.