Description

(S)-2-[(Carbobenzoxy)Amino]-Octanoic Acid is a chiral, N-protected amino acid derivative, specifically the Cbz-protected form of (S)-2-Aminooctanoic acid. This compound is a crucial building block in the synthesis of peptides and peptidomimetics, offering high enantiomeric purity for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including enzyme inhibitors and bioactive peptides. Its defined stereochemistry and protective group make it an essential intermediate for creating complex molecular architectures with precise biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological disorders.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS) to construct specific peptide sequences.
• Protease Inhibitor Development: Used in the design and synthesis of potential inhibitors for various proteases, leveraging its lipophilic side chain for targeted binding.
• Bioconjugation & Labeling: The carboxylic acid and protected amine functionalities allow for selective conjugation to other molecules, proteins, or solid supports for biochemical studies.
• Chemical Biology Research: Employed as a tool compound to study enzyme-substrate interactions and to incorporate non-natural amino acid motifs into peptides.
• Material Science: Potential use in the synthesis of specialized polymers and dendrimers where chiral centers and specific functional groups are required.

Basic Information

Product Name	(S)-2-[(Carbobenzoxy)Amino]-Octanoic Acid
CAS No.	119817-31-1
Molecular Formula	C₁₆H₂₃NO₄
Molecular Weight	293.36 g/mol
Synonyms	(S)-2-(Benzyloxycarbonylamino)octanoic acid; (S)-N-Carbobenzoxy-2-aminocaprylic acid; (S)-N-Cbz-2-Aminooctanoic Acid; (S)-N-[(Benzyloxy)carbonyl]norleucine; Z-(S)-Aminooctanoic Acid; (S)-2-[(Benzyloxycarbonyl)amino]octanoic acid; (S)-2-(Cbz-amino)octanoic acid; N-α-Cbz-(S)-2-Aminooctanoic Acid
EINECS	Contact for details

Quality Control

Our (S)-2-[(Carbobenzoxy)Amino]-Octanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, critical for sensitive pharmaceutical applications. Standard testing includes HPLC for assay and purity, chiral analysis to confirm enantiomeric excess, and spectroscopic identification (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We can support development projects with custom purity grades and analytical data packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.