Description

Fmoc-Thr(Tbu)-Odhbt CAS NO 119767-84-9 is a high-purity, protected amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly for complex or therapeutic sequences. It is an essential building block for pharmaceutical R&D, biotechnology applications, and the production of peptide-based active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated, sequential assembly of peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and development of novel peptide therapeutics, hormones, and vaccines.
• Bioconjugation and Labeling: Serves as a precursor for creating peptide conjugates for diagnostic probes or drug delivery systems.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• API Intermediate Manufacturing: A critical raw material in the cGMP production of peptide-based active pharmaceutical ingredients.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Fmoc-Thr(Tbu)-Odhbt
CAS No.	119767-84-9
Molecular Formula	C28H34N2O7
Molecular Weight	510.58 g/mol
Synonyms	Fmoc-Thr(O-t-Bu)-ODhbt; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(tert-butyl)-L-threonine 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl Ester; Fmoc-O-tert-butyl-L-threonine Dhbt Ester; Fmoc-Thr(tBu)-ODhbt Ester; Fmoc-L-Threonine(O-t-butyl) Dhbt Ester; 1,2,3-Benzotriazin-4(3H)-one, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl][(2S,3R)-3-[(1,1-dimethylethoxy)methyl]-2-hydroxy-1-oxobutyl]amino]-3,4-dihydro-; Fmoc-Thr(But)-ODhbt
EINECS	Contact for details

Quality Control

Our Fmoc-Thr(Tbu)-Odhbt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and material can be supplied to meet specific research or cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.