Description

p-[Tetrahydropyran-2-Yloxy]Phenylacetylene is a specialized organic building block featuring a terminal alkyne group protected by a tetrahydropyranyl (THP) ether. This compound is of significant value in synthetic organic chemistry, particularly for its role in constructing complex molecular architectures via cross-coupling reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, especially those requiring alkyne functionalization for click chemistry or Sonogashira coupling.
• Agrochemical Research: Used in the development of new active ingredients with specific biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	p-[Tetrahydropyran-2-Yloxy]Phenylacetylene
CAS No.	119754-16-4
Molecular Formula	C13H14O2
Molecular Weight	202.25 g/mol
Synonyms	4-(2-Tetrahydropyranyloxy)phenylacetylene; 4-(Tetrahydro-2H-pyran-2-yloxy)phenylacetylene; 1-[4-(Tetrahydro-2H-pyran-2-yloxy)phenyl]ethyne; 4-(THP-O)C6H4C≡CH; p-(THP-O)Phenylacetylene; 4-(Tetrahydropyran-2-yloxy)benzeneacetylene; 4-(2H-Pyran-2-yloxy)phenylacetylene, tetrahydro-
EINECS	Contact for details

Quality Control

Our p-[Tetrahydropyran-2-Yloxy]Phenylacetylene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 95.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.