Description

Somatotropin Sulfoxide CAS NO 119632-29-0 is a chemically modified derivative of somatotropin (growth hormone), where a sulfur-containing amino acid residue has been oxidized to a sulfoxide. This modification is of significant interest in biochemical and pharmaceutical research for studying protein structure-function relationships, stability, and post-translational modifications. It serves as a critical reference standard and intermediate for researchers and developers in the fields of endocrinology, biotechnology, and advanced therapeutic peptide development.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of somatotropin and its derivatives in method development and validation.
• Biochemical Research: A key tool for investigating the impact of methionine oxidation on the biological activity, conformation, and stability of protein therapeutics.
• Process Development: Employed as a model compound in the development and optimization of purification, formulation, and analytical techniques for recombinant protein products.
• Quality Control & Stability Studies: Acts as a known impurity or degradation marker in the stability-indicating assays for somatotropin-based drug products.
• Academic Research: Utilized in university and institutional labs for fundamental studies in protein chemistry, oxidative stress, and hormone signaling pathways.

Basic Information

Product Name	Somatotropin Sulfoxide
CAS No.	119632-29-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Oxidized Somatotropin; Growth Hormone Sulfoxide; hGH Sulfoxide; Somatropin Sulfoxide; Recombinant Human Growth Hormone Sulfoxide; Methionine-oxidized Somatotropin; PST Sulfoxide
EINECS	Contact for details

Quality Control

Our Somatotropin Sulfoxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity and structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unspecified impurity ≤ 2.0%
Water Content (Karl Fischer)	≤ 5.0%
Biological Activity	To be determined by end-user assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.