Description

1H-Pyrrole-2-Carbonitrile, 4-Acetyl-1-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring high-purity intermediates for research and development, such as medicinal chemistry and material science, are the primary users of this nitrile-substituted pyrrole derivative.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Dye and Pigment Synthesis: Employed in the production of specialized heterocyclic dyes and functional colorants.
• Academic & Contract Research: A valuable reagent for methodological development and exploration of new chemical spaces in university and CRO laboratories.
• Ligand Synthesis for Catalysis: Used to construct complex nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	1H-Pyrrole-2-Carbonitrile, 4-Acetyl-1-Methyl- (9Ci)
CAS No.	119580-83-5
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	4-Acetyl-1-methyl-1H-pyrrole-2-carbonitrile; 1-Methyl-4-acetylpyrrole-2-carbonitrile; 2-Cyano-1-methyl-4-acetylpyrrole; 4-Acetyl-1-methylpyrrole-2-carbonitrile; 1-Methyl-4-acetyl-2-cyanopyrrole; 4-Acetyl-1-methyl-2-cyanopyrrole; (4-Acetyl-1-methyl-1H-pyrrol-2-yl)methanenitrile
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonitrile, 4-Acetyl-1-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.