Description

2-(tert-Butoxycarbonylamino)Pent-4-Enoic Acid is a protected amino acid derivative, specifically a Boc-protected 4-pentenoic acid analog. This compound is a crucial chiral building block in organic synthesis, valued for its dual functionality that allows for selective chemical transformations. It is primarily utilized by pharmaceutical and biotechnology research organizations for the synthesis of complex molecules, including peptide mimetics, active pharmaceutical ingredients (APIs), and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs) and therapeutic peptides.
• Peptidomimetic Synthesis: Used to incorporate unnatural amino acid residues with an alkene handle for further functionalization via click chemistry or cross-metathesis.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged molecules used in proteomics and target identification studies.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic complexes.
• Academic & Industrial R&D: A versatile reagent in medicinal chemistry programs for structure-activity relationship (SAR) exploration and library synthesis.
• Custom Synthesis: Provides a foundation for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	2-(tert-Butoxycarbonylamino)Pent-4-Enoic Acid
CAS No.	119479-32-2
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	Boc-4-Pentenylglycine; (S)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic Acid; N-Boc-2-Amino-4-pentenoic Acid; 4-Pentenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-; Boc-DL-2-Amino-4-pentenoic Acid; N-(tert-Butoxycarbonyl)-4-pentenylglycine; 2-(Boc-amino)-4-pentenoic acid
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonylamino)Pent-4-Enoic Acid is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Standard quality control includes identity confirmation by spectroscopic methods and purity assessment by chromatography. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (where applicable), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.