Description

Hemoglobin F Seattle CAS NO 119322-29-1 is a specific variant of fetal hemoglobin, a critical protein for oxygen transport. This compound is of significant interest in biochemical research and diagnostic development due to its unique structural properties. It is primarily utilized by researchers in hematology, clinical diagnostics, and pharmaceutical development for studying hemoglobinopathies and developing targeted therapeutic and analytical applications.

Application

• Biochemical Research Standard: Used as a reference material in studies of fetal hemoglobin structure, function, and genetic variants.
• Diagnostic Assay Development: Serves as a key component in the calibration and validation of diagnostic tests for sickle cell disease and thalassemia.
• Therapeutic Protein Studies: Employed in research focused on developing hemoglobin-based oxygen carriers (HBOCs) and gene therapies.
• Clinical Laboratory Testing: Used as a control or calibrator in high-performance liquid chromatography (HPLC) and mass spectrometry methods for hemoglobin analysis.
• Educational & Training Material: Provides a specific example for academic and professional training in clinical chemistry and molecular biology.

Basic Information

Product Name	Hemoglobin F Seattle
CAS No.	119322-29-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F Seattle; Fetal Hemoglobin Seattle; γ-Globin Variant Seattle; Hemoglobin F (Seattle); Gly->Asp variant at γ-136; HbF Seattle variant; Fetal hemoglobin (Seattle type)
EINECS	Contact for details

Quality Control

Our Hemoglobin F Seattle is produced and handled under stringent quality protocols suitable for research and diagnostic applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stability. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation, and other relevant parameters is available upon request to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For extended storage, consider aliquoting and freezing at -20°C or below under inert conditions.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/MS)	Conforms to standard for Hb F Seattle
Purity (HPLC)	≥ 95%
Solubility	Soluble in aqueous buffers
Protein Content (Biuret)	≥ 90%
Moisture Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.