Description

2-Thiophenecarbonitrile, 5-Formyltetrahydro-, trans- (9Ci) is a specialized heterocyclic building block featuring both nitrile and formyl functional groups on a saturated thiophene ring. This unique molecular architecture makes it a valuable intermediate for synthesizing complex pharmacologically active compounds and advanced materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	2-Thiophenecarbonitrile, 5-Formyltetrahydro-, trans- (9Ci)
CAS No.	119292-54-5
Molecular Formula	C6H7NOS
Molecular Weight	141.19 g/mol
Synonyms	trans-5-Formyltetrahydro-2-thiophenecarbonitrile; (2R,5R)-5-Formyltetrahydrothiophene-2-carbonitrile; (2S,5S)-5-Formyltetrahydrothiophene-2-carbonitrile; Tetrahydro-5-formyl-2-thiophenecarbonitrile, trans-; 5-Formyltetrahydrothiophene-2-carbonitrile; 2-Cyano-5-formyltetrahydrothiophene
EINECS	Contact for details

Quality Control

Every batch of 2-Thiophenecarbonitrile, 5-Formyltetrahydro-, trans- (9Ci) is produced under strict quality management protocols. We provide comprehensive analytical data including HPLC purity, NMR, and MS to ensure identity and consistency for your critical research and development work. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.