Description

Gastrin Releasing Peptide, Rat is a synthetic peptide analog of the endogenous mammalian hormone, specifically the rat isoform. This high-purity biochemical is essential for advanced research into neuroendocrine signaling, gastrointestinal physiology, and related receptor studies. It is a critical reagent for pharmaceutical R&D, academic institutions, and biotechnology companies focused on metabolic disorders and cancer research.

Application

• Neuroscientific Research: Used as a specific agonist to study the role of GRP in the central and peripheral nervous systems.
• Gastrointestinal Physiology Studies: Investigates the peptide's function in stimulating gastrin release and regulating gastric acid secretion.
• Receptor Binding & Signal Transduction Assays: Serves as a standard ligand for characterizing Bombesin Receptor Subtype-2 (BB2) affinity and activity.
• In Vitro & Ex Vivo Model Systems: Applied in cell culture and tissue bath experiments to elucidate autocrine and paracrine signaling pathways.
• Biomarker and Diagnostic Development: Potential use in the development of assays for conditions involving GRP pathway dysregulation.
• Pharmaceutical Screening: A key tool in drug discovery programs targeting the GRP receptor for therapeutic intervention.

Basic Information

Product Name	Gastrin Releasing Peptide, Rat
CAS No.	119290-92-5
Molecular Formula	C115H168N32O33S
Molecular Weight	2462.8 g/mol
Synonyms	Rat GRP; GRP (14-27), rat; Neuromedin C; Gastrin-releasing peptide (rat); pGlu-Pro-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; Litorin; BB2 receptor agonist
EINECS	Contact for details

Quality Control

Our Gastrin Releasing Peptide, Rat is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot is subjected to comprehensive analytical testing, including reversed-phase HPLC for purity assessment and mass spectrometry for identity confirmation. A Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.