Description

Antithrombin Iii Avranches is a high-purity, biologically active serine protease inhibitor that plays a critical role in the regulation of the blood coagulation cascade. This compound is essential for research and development in the life sciences, offering a key reagent for studying thrombosis, hemostasis, and related therapeutic pathways. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic institutions focused on cardiovascular disease, hematology, and anticoagulant drug discovery.

Application

• Biopharmaceutical Research: Critical reagent for studying the mechanisms of blood coagulation and developing novel anticoagulant therapies.
• Diagnostic Kit Manufacturing: Used as a standard or key component in assays for measuring antithrombin III levels in clinical diagnostics.
• Enzyme Inhibition Studies: Serves as a specific inhibitor for thrombin and other coagulation factors (Xa, IXa) in biochemical research.
• Reference Standard: Acts as a high-purity standard for quality control in the production of therapeutic proteins and plasma-derived products.
• Cell Culture & Biomedical Research: Employed in experimental models to investigate the role of antithrombin in inflammation, angiogenesis, and cancer metastasis.

Basic Information

Product Name	Antithrombin Iii Avranches
CAS No.	119214-24-3
Molecular Formula	Contact for details
Molecular Weight	~58 kDa
Synonyms	Antithrombin III; ATIII; Serpin C1; Heparin Cofactor I; Antithrombin; AT 3; Antithrombin-3; Antithrombin Avranches; Antithrombin III Human; AT-III
EINECS	Contact for details

Quality Control

Our Antithrombin Iii Avranches is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is characterized for purity, potency, and identity using advanced analytical techniques. Certificates of Analysis (COA) detailing specifications such as activity (IU/mg), purity by SDS-PAGE and HPLC, endotoxin levels, and sterility are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant when applicable.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR / HPLC)	Conforms to Standard
Purity (SDS-PAGE)	≥ 95%
Assay (Biological Activity)	≥ 5.0 IU/mg
Endotoxin	< 1.0 EU/mg
Protein Content	≥ 90%
Solubility	Soluble in water or appropriate buffer
Residual Moisture (KF)	< 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.