Description

n-(2-Propenal)Serine is a specialized amino acid derivative where the serine side chain is modified with an acrolein (2-propenal) moiety. This functionalization makes it a valuable building block in organic synthesis and pharmaceutical research, particularly for introducing reactive aldehyde groups into peptide chains or other molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical developers working on targeted drug delivery systems, bioconjugation, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates and targeted therapeutics.
• Bioconjugation Reagent: Used to attach drugs, probes, or other molecules to proteins, antibodies, or peptides via its reactive aldehyde group.
• Peptide Modification: Enables site-specific functionalization of serine residues within synthetic peptides.
• Cross-linking Agent: Facilitates the creation of cross-linked biomaterials or polymer networks in biochemical research.
• Chemical Biology Research: A tool for studying protein interactions, enzyme mechanisms, and cellular processes.
• Material Science: Potential monomer or modifier in the development of functionalized polymers with specific biological activity.

Basic Information

Product Name	n-(2-Propenal)Serine
CAS No.	119206-60-9
Molecular Formula	C6H9NO4
Molecular Weight	159.14 g/mol
Synonyms	N-Acryloylserine; Serine, N-(1-oxo-2-propenyl)-; N-(1-Oxo-2-propenyl)serine; 2-Amino-3-hydroxy-N-(2-propenoyl)propanoic acid; Acrolein-serine adduct; N-(2-Propenoyl)serine; (S)-2-Amino-3-hydroxy-N-acryloylpropanoic acid; Acryloyl-L-serine
EINECS	Contact for details

Quality Control

Our n-(2-Propenal)Serine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) principles for advanced intermediates, and specifications can be aligned with client requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.