Description

3-(Acetylthio)Propionitrile is a versatile sulfur-containing nitrile building block used in advanced organic synthesis. This compound is valued for its ability to introduce both thioester and nitrile functionalities, enabling the construction of complex heterocycles and pharmaceutical intermediates. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing thiazole, thiadiazole, and other sulfur-containing heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific sulfur-nitrogen motifs.
• Ligand and Catalyst Precursor: Serves as a precursor for ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of functional polymers and advanced materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Useful for synthesizing probes and linkers for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-(Acetylthio)Propionitrile
CAS No.	119174-33-3
Molecular Formula	C5H7NOS
Molecular Weight	129.18 g/mol
Synonyms	3-(Acetylthio)propanenitrile; 3-Acetylthiopropionitrile; Acetyl 3-cyanopropyl sulfide; 3-Cyanopropyl thioacetate; 3-(Acetylsulfanyl)propanenitrile; Acetylthiopropanenitrile; β-Acetylthiopropionitrile; NSC 405124
EINECS	Contact for details

Quality Control

Our 3-(Acetylthio)Propionitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. This material is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.