Description

Poly(D-Glu, D-Lys) Hydrobromide is a synthetic polypeptide derivative composed of D-glutamic acid and D-lysine residues, supplied as the hydrobromide salt. This compound is a critical research-grade material valued for its unique stereochemistry and defined polymeric structure, which provides a stable and reproducible platform for advanced biochemical studies. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on immunology, peptide-based drug delivery systems, and the study of biomimetic materials.

Application

• Immunological Research: Used as a model antigen or immunomodulator in studies of immune response mechanisms due to its defined polymeric structure.
• Drug Delivery Systems: Serves as a carrier or scaffold in the development of novel peptide-based delivery platforms for therapeutic agents.
• Biomaterial Science: Investigated for creating synthetic extracellular matrices or hydrogels that mimic natural tissue environments.
• Bioconjugation Studies: Acts as a backbone for attaching functional groups, dyes, or targeting ligands in bioconjugation chemistry.
• Standard Reference Material: Employed as a calibration standard or control in analytical methods for characterizing synthetic polypeptides.
• Structure-Activity Relationship (SAR) Studies: Provides a well-defined polymeric model to study the relationship between peptide structure and biological function.

Basic Information

Product Name	Poly(D-Glu, D-Lys) Hydrobromide
CAS No.	119039-80-4
Molecular Formula	(C11H18N2O5·HBr)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(D-Glutamic Acid-co-D-Lysine) Hydrobromide; Poly(D-Glu, D-Lys) HBr; D-Glutamic Acid and D-Lysine Copolymer Hydrobromide; PDGL HBr; Poly(D-Glu-D-Lys)·HBr; Poly(D-Glu50, D-Lys50) Hydrobromide; Poly(D-Glu-Lys) HBr; Synthetic Polypeptide Hydrobromide Salt
EINECS	Contact for details

Quality Control

Our Poly(D-Glu, D-Lys) Hydrobromide is produced under controlled conditions to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot undergoes rigorous analytical testing, including spectroscopic identification and purity assessment. A comprehensive Certificate of Analysis (COA) detailing specific parameters such as amino acid composition, molecular weight distribution, and residual solvent content is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Amino Acid Ratio (Glu:Lys)	As specified (e.g., 50:50)
Assay (Content)	≥ 95% (by HPLC or elemental analysis)
Molecular Weight (Average)	As specified (e.g., 5,000 - 50,000 Da)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Bromide Content	Consistent with theoretical value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.