Description

Ethanone, 1-(2-Fluoro-1-Hydroxycyclohexyl)-, trans- (9Ci) CAS NO 119030-21-6 is a specialized fluorinated ketone derivative featuring a cyclohexyl ring with hydroxyl and fluoro substituents. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, particularly for introducing fluorine atoms and complex stereochemistry into target molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of fluorinated drug candidates, including potential CNS agents and anti-infectives.
• Agrochemical Synthesis: Building block for creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Advanced Material Research: Used in the synthesis of specialty monomers or ligands for catalysts and functional polymers.
• Asymmetric Catalysis: Serves as a substrate or a precursor to ligands in stereoselective catalytic reactions.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the properties and reactivity of organofluorine molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API development projects.

Basic Information

Product Name	Ethanone, 1-(2-Fluoro-1-Hydroxycyclohexyl)-, trans- (9Ci)
CAS No.	119030-21-6
Molecular Formula	C8H13FO2
Molecular Weight	160.19 g/mol
Synonyms	trans-1-(2-Fluoro-1-hydroxycyclohexyl)ethanone; 1-(2-Fluoro-1-hydroxycyclohexyl)ethanone, trans-; 2-Fluoro-1-(1-hydroxycyclohexyl)ethanone (trans isomer); 119030-21-6; trans-2-Fluoro-1-hydroxycyclohexyl methyl ketone; (1R,2S)-1-(2-Fluoro-1-hydroxycyclohexyl)ethanone (relative stereochemistry); Fluorocyclohexyl hydroxy ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Fluoro-1-Hydroxycyclohexyl)-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.