Description

2-Azetidinone, 3-Acetyl-1,3-Dimethyl-4-Methylene- (9Ci) is a specialized β-lactam derivative, a key structural motif in medicinal chemistry. This compound serves as a versatile and high-value synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for constructing complex molecules, particularly in the synthesis of new antibiotics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel β-lactam antibiotics and other pharmacologically active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates targeting bacterial infections.
• Organic Synthesis: Serves as a reactive scaffold for constructing complex heterocyclic systems and fused ring structures in academic and industrial laboratories.
• Biochemical Tool Compound: Potential use in biochemical assays to study β-lactamase enzyme activity and inhibition mechanisms.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, low-volume specialty chemicals for advanced material science.

Basic Information

Product Name	2-Azetidinone, 3-Acetyl-1,3-Dimethyl-4-Methylene- (9Ci)
CAS No.	118987-40-9
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	3-Acetyl-1,3-dimethyl-4-methylenazetidin-2-one; 3-Acetyl-1,3-dimethyl-4-methylene-2-azetidinone; 4-Methylene-3-acetyl-1,3-dimethylazetidin-2-one; 1,3-Dimethyl-3-acetyl-4-methylene-2-azetidinone; 3-Acetyl-1,3-dimethyl-4-methylen-2-azetidinon; β-Lactam derivative, acetyl-dimethyl-methylene substituted
EINECS	Contact for details

Quality Control

We supply this high-purity synthetic intermediate under a stringent quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency, supporting reproducible research and development outcomes. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR/NMR), and impurity profile is provided with every shipment. Our quality protocols are designed to meet the exacting standards of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.