Description

Vd3-D6 CAS NO 118584-54-6 is a deuterated form of Vitamin D3, a critical compound in pharmaceutical and biochemical research. This high-purity, isotopically labeled standard is essential for ensuring analytical accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by research institutions, pharmaceutical development labs, and contract research organizations (CROs) engaged in advanced vitamin D research, drug metabolism and pharmacokinetics (DMPK) studies, and clinical diagnostics.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard for the accurate measurement of endogenous Vitamin D3 and its metabolites in biological matrices.
• Drug Metabolism Studies (DMPK): Used as a tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of Vitamin D3 and related analogs in preclinical research.
• Clinical Research & Diagnostics: Enables precise quantification in human serum/plasma for studies on Vitamin D deficiency, bone health, and related endocrine disorders.
• Pharmaceutical Quality Control: Employed in the assay and impurity profiling of Vitamin D3-based active pharmaceutical ingredients (APIs) and finished drug products.
• Nutritional Science Research: Facilitates stable isotope dilution analysis in studies examining Vitamin D3 bioavailability from fortified foods and supplements.
• Biochemical Pathway Analysis: Acts as a tool for elucidating complex metabolic pathways and enzymatic transformations involving Vitamin D.

Basic Information

Product Name	Vd3-D6
CAS No.	118584-54-6
Molecular Formula	C₂₇H₄₀D₆O
Molecular Weight	392.68 g/mol
Synonyms	Vitamin D3-d6; Cholecalciferol-d6; (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol-d6; 7-Dehydrocholesterol-d6 derivative; Calciol-d6; Colecalciferol-d6; Deuterated Vitamin D3; [²H₆]-Vitamin D3
EINECS	Contact for details

Quality Control

Our Vd3-D6 is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing assay, isotopic purity, and impurity profiles to support your research and regulatory submissions. Our commitment to traceability and consistency ensures reliable performance as a critical reference material.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as indicated on the label/Certificate of Analysis. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or solution
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Solvent (if applicable)	Ethanol, Toluene, or specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.