Description

Fmoc-Asp(o-1-Ada)-Oh is a specialized, protected amino acid derivative used in solid-phase peptide synthesis (SPPS). This compound is critical for the controlled introduction of aspartic acid with a specific side-chain protecting group, enabling the synthesis of complex peptides and proteins. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the Fmoc-strategy synthesis of complex peptide sequences.
• Pharmaceutical R&D: Used in the research and development of novel therapeutic peptides and peptidomimetics targeting various diseases.
• Bioconjugation: Serves as a precursor for creating peptide-based conjugates for drug delivery systems and diagnostic probes.
• Chemical Biology: Employed in the study of protein-protein interactions and enzyme mechanisms through the incorporation of modified amino acids.
• API Intermediate: Acts as a critical intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for peptide drugs.

Basic Information

Product Name	Fmoc-Asp(o-1-Ada)-Oh
CAS No.	118534-81-9
Molecular Formula	C30H35NO6
Molecular Weight	505.60 g/mol
Synonyms	Fmoc-L-aspartic acid α-1-adamantyl ester; N-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid 1-adamantyl ester; Fmoc-Asp(O-Ada)-OH; Fmoc-Asp(1-Ada)-OH; Nα-Fmoc-L-aspartic acid 1-adamantyl ester; Fmoc-Asp-O-1-Ada-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanedioic acid 5-(1-adamantyl) ester; Fmoc-Asp(1-Adamantyl)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Asp(o-1-Ada)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability for our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.