Description

2,6-Bis(Trifluoromethyl)Bromobenzene is a high-value, multi-functional fluorinated aromatic building block. This compound is essential for introducing both bromine and trifluoromethyl groups into complex molecular architectures, enabling precise tuning of electronic properties, lipophilicity, and metabolic stability. It is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, ligands, and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced bioavailability and target binding.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves compound stability and efficacy.
• Ligand & Catalyst Development: Serves as a versatile building block for constructing sophisticated ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, where fluorination modifies charge transport properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl structures.
• Fluorine Chemistry Exploration: A critical reagent for studying structure-activity relationships (SAR) and introducing fluorine atoms into complex molecules.

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Bromobenzene
CAS No.	118527-30-3
Molecular Formula	C9H3BrF6
Molecular Weight	305.02 g/mol
Synonyms	1-Bromo-2,6-bis(trifluoromethyl)benzene; 2,6-Bis(trifluoromethyl)phenyl bromide; Bromo-2,6-bis(trifluoromethyl)benzene; 2,6-Di(trifluoromethyl)bromobenzene; α,α,α,α',α',α'-Hexafluoro-2-bromoxylene; Benzene, 1-bromo-2,6-bis(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2,6-Bis(Trifluoromethyl)Bromobenzene is manufactured and tested under a strict quality management system. We guarantee high-purity material suitable for demanding synthetic applications. Comprehensive analytical testing, including GC, HPLC, and NMR, is performed to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.