Description

Tetra-o-Acetyl-A-Mannosyl-Fmocserine CAS NO 118358-80-8 is a sophisticated, protected amino acid derivative designed for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise, high-yield incorporation of serine with a mannose moiety into peptide chains. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in the development of glycopeptides, peptide-based therapeutics, and complex biomolecules.

Application

• Glycopeptide Synthesis: A key building block for the automated synthesis of glycopeptides, enabling the study of glycosylation effects on peptide function and stability.
• Pharmaceutical Research: Used in the research and development of novel peptide-based drugs, vaccines, and diagnostic agents.
• Bioconjugation: Facilitates the site-specific conjugation of peptides to other molecules, such as drugs, dyes, or polymers, for creating targeted biotherapeutics.
• Chemical Biology Probes: Essential for synthesizing labeled or modified peptides used as probes to study protein-protein interactions and enzyme mechanisms.
• Antibiotic Development: Applied in the synthesis of complex peptide antibiotics where specific glycosylation patterns are crucial for bioactivity.
• Custom Peptide Services: A vital reagent for CROs and CDMOs offering custom peptide synthesis services to the biotech and academic sectors.

Basic Information

Product Name	Tetra-o-Acetyl-A-Mannosyl-Fmocserine
CAS No.	118358-80-8
Molecular Formula	C32H35NO13
Molecular Weight	641.62 g/mol
Synonyms	Fmoc-Ser(Ac4-α-D-Man)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-L-serine; Fmoc-Ser(Ac4-Man)-OH; Fmoc-L-Serine, O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-, 9-fluorenylmethyl ester; Ac4Manα-Ser(Fmoc)-OH; Fmoc-Ser(α-Ac4Man)-OH; Glycosylated Fmoc-Serine derivative
EINECS	Contact for details

Quality Control

Every batch of Tetra-o-Acetyl-A-Mannosyl-Fmocserine is produced and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.