Description

Fentanyl-D5 Citrate 100 Ug/Ml In Methanol is a certified reference material (CRM) and stable isotopically labeled internal standard, essential for high-precision analytical quantification. This product is critical for ensuring accuracy and reliability in sensitive mass spectrometry-based analyses, providing a definitive benchmark for method validation and quality control. It is primarily required by analytical laboratories, forensic science facilities, and pharmaceutical R&D departments engaged in pharmacokinetic studies, clinical toxicology, and drug metabolism research.

Application

• Quantitative Mass Spectrometry: Serves as an internal standard for the accurate quantification of fentanyl and its analogs in complex biological matrices (e.g., plasma, urine, tissue).
• Forensic Toxicology: Used in the confirmation and precise measurement of fentanyl concentrations in post-mortem and human performance testing samples.
• Pharmaceutical Research: Enables precise pharmacokinetic and metabolism studies of fentanyl in drug development and clinical trials.
• Clinical Laboratory Testing: Supports high-complexity testing for therapeutic drug monitoring and overdose diagnosis in hospital settings.
• Method Development & Validation: Acts as a critical component for developing, optimizing, and validating LC-MS/MS and GC-MS methods according to FDA, EMA, and other regulatory guidelines.
• Quality Control & Assurance: Provides a traceable reference point for in-house quality control programs in testing laboratories to ensure data integrity.

Basic Information

Product Name	Fentanyl-D5 Citrate 100 Ug/Ml In Methanol
CAS No.	118357-30-5
Molecular Formula	C28H36D5N2O8
Molecular Weight	532.7 g/mol (approx.)
Synonyms	Fentanyl-d5 citrate; Deuterated Fentanyl Citrate; N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide-d5 citrate; Fentanyl (phenyl-d5) citrate; Fentanyl-D5 (citrate salt); Fentanyl Internal Standard; CRM for Fentanyl Analysis; Isotopically Labeled Fentanyl.
EINECS	Contact for details

Quality Control

Every batch of this certified reference material is produced and analyzed under strict quality management systems. Certificates of Analysis (COA) are provided, detailing the certified concentration, isotopic purity, and solvent verification via validated methods such as HPLC and LC-MS/MS. Our quality commitment ensures compliance with the standards expected for forensic and clinical reference materials, supporting data defensibility in regulated environments.

Storage

Preserve in the original tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Due to its high volatility and the methanol solvent, ensure proper ventilation and handle in accordance with laboratory safety protocols for flammable solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless solution
Concentration	100 µg/mL ± 5% in Methanol
Certified Value	Provided on COA
Isotopic Purity (D5)	≥ 98%
Chemical Purity (HPLC)	≥ 99%
Solvent Verification	Methanol (by GC)
Stability	Stable until expiry date when stored as directed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.