Description

Fentanyl-D5 is a deuterium-labeled internal standard of the potent synthetic opioid fentanyl, specifically designed for analytical and research applications. This stable isotopically labeled compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry. It is a critical tool for forensic laboratories, pharmaceutical researchers, and clinical toxicologists requiring precise measurement of fentanyl and its analogs in complex matrices.

Application

• Quantitative Mass Spectrometry: Serves as an internal standard for the accurate quantification of fentanyl in biological samples (e.g., blood, urine, tissue) and pharmaceutical formulations.
• Forensic Toxicology: Used in method development and routine analysis for post-mortem and DUID (Driving Under the Influence of Drugs) casework to determine fentanyl concentrations.
• Pharmacokinetic & Metabolism Studies: Enables precise tracking of fentanyl absorption, distribution, metabolism, and excretion (ADME) in research settings.
• Pharmaceutical Quality Control: Applied in the analysis of active pharmaceutical ingredients (API) and finished dosage forms to ensure potency and purity.
• Reference Material for Calibration: Used to prepare calibration curves and validate analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Research on Illicit Drug Adulteration: Facilitates the detection and quantification of fentanyl in street drug samples and counterfeit medications.

Basic Information

Product Name	Fentanyl-D5
CAS No.	118357-29-2
Molecular Formula	C22H23D5N2O
Molecular Weight	341.50 g/mol
Synonyms	N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide-d5; Fentanyl-d5; [2H5]-Fentanyl; Deuterated Fentanyl (d5); Fentanyl Internal Standard; 1-Phenethyl-4-(N-phenylpropionamido)piperidine-d5; N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide-d5
EINECS	Contact for details

Quality Control

Every batch of Fentanyl-D5 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) specifying purity, isotopic enrichment, and solvent content is provided with each shipment to ensure traceability and compliance with your research or analytical method requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.