Description

Methadone-D3 Hydrochloride 98 Atom %*D--Dea Schedule CAS NO 118357-25-8 is a high-purity, deuterium-labeled internal standard essential for precise quantitative analysis in mass spectrometry. This compound is critical for ensuring analytical accuracy and regulatory compliance in sensitive testing environments. It is primarily required by analytical laboratories, forensic toxicology departments, and pharmaceutical R&D facilities engaged in method development and validation for opioid detection and metabolism studies.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of methadone and its metabolites in biological matrices (e.g., blood, urine, plasma).
• Method Development and Validation in forensic, clinical, and workplace drug testing laboratories to ensure accuracy and meet regulatory standards.
• Pharmacokinetic and Metabolism Studies in pharmaceutical research to track and quantify drug levels and metabolic pathways.
• Quality Control and Reference Standard production for manufacturers of diagnostic kits and certified reference materials.
• Use in Doping Control analysis to detect and confirm the presence of prohibited substances in sports.
• Supporting Research in neuropharmacology and addiction medicine, providing a stable isotopic tracer for advanced studies.

Basic Information

Product Name	Methadone-D3 Hydrochloride 98 Atom %*D--Dea Schedule CAS NO 118357-25-8
CAS No.	118357-25-8
Molecular Formula	C21H24D3ClNO
Molecular Weight	348.93 g/mol (approx.)
Synonyms	(±)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone-d3 Hydrochloride; Methadone-d3 HCl; DL-Methadone-d3 Hydrochloride; 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine-d3 Hydrochloride; Methadone-D3 (Deuterated); Racemic Methadone-d3 Hydrochloride; 118357-25-8; Methadone Internal Standard-d3
EINECS	Contact for details

Quality Control

Our Methadone-D3 Hydrochloride is manufactured under strict quality systems to ensure the highest isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and Mass Spectrometry, to confirm the 98 Atom % D enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Due to its hygroscopic nature, the product should be handled in a low-humidity environment and the container kept sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98%
Chemical Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.