Description

Dl-5-Fluorolysine Hydrochloride CAS NO 118101-18-1 is a fluorinated derivative of the essential amino acid lysine, where a fluorine atom is introduced at the 5-position of the carbon chain. This structural modification makes it a valuable non-natural amino acid analog, primarily utilized as a biochemical tool in life science research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of medicinal chemistry, proteomics, and metabolic pathway analysis. The compound serves as a critical building block for studying enzyme mechanisms and developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly those targeting enzymes where lysine plays a key role.
• Biochemical Research: Acts as a substrate analog or inhibitor in enzymatic studies to investigate the function and mechanism of lysine-specific enzymes.
• Proteomics & Labeling: Employed in the development of chemical probes for protein labeling and activity-based protein profiling (ABPP).
• Metabolic Pathway Analysis: Serves as a tracer or modulator in metabolic studies to understand fluorine incorporation and lysine metabolism.
• Peptide Synthesis: Incorporated into custom peptides to alter their stability, binding properties, or biological activity for research purposes.
• Antibiotic Research: Investigated for its potential role in the development of new antimicrobial agents that target bacterial cell wall synthesis.

Basic Information

Product Name	Dl-5-Fluorolysine Hydrochloride
CAS No.	118101-18-1
Molecular Formula	C6H14ClFN2O2
Molecular Weight	200.64 g/mol
Synonyms	5-Fluorolysine hydrochloride; DL-5-Fluorolysine HCl; (±)-5-Fluorolysine hydrochloride; 2,6-Diamino-5-fluorohexanoic acid hydrochloride; 5-Fluoro-L-lysine hydrochloride (racemic); 5-Fluoro-DL-lysine monohydrochloride; 5-Fluorolysine HCl; 5-Fluoronorleucine derivative
EINECS	Contact for details

Quality Control

Our Dl-5-Fluorolysine Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports applications requiring high-purity biochemical building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic mixture (DL-form)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.