Description

Tnpal-Galactocerebroside CAS NO 118099-48-2 is a chemically modified cerebroside derivative, specifically a trinitrophenylated form of galactocerebroside, designed for advanced biochemical research and diagnostic applications. This compound is a critical reagent for studying lipid-protein interactions, membrane dynamics, and immune responses within the nervous system. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on neuroscience, autoimmune disorders, and lipidomics.

Application

• Biochemical Research: As a specific antigen or hapten for studying antibody binding, lipid rafts, and myelin structure in neurological models.
• Diagnostic Development: Key component in the development of immunoassays and ELISA kits for detecting anti-glycolipid antibodies associated with autoimmune neuropathies like Guillain-Barré syndrome.
• Neuroscience Studies: Used to investigate the role of galactocerebrosides in cell signaling, apoptosis, and the pathogenesis of demyelinating diseases such as multiple sclerosis.
• Pharmaceutical Screening: Employed in high-throughput screening assays to identify potential therapeutic compounds that modulate glycolipid-mediated immune or cellular responses.
• Lipidomics & Metabolomics: Serves as a reference standard or internal standard for the qualitative and quantitative analysis of complex lipid mixtures using techniques like mass spectrometry.
• Vaccine Adjuvant Research: Investigated for its potential immunomodulatory properties in conjugate vaccine formulations targeting specific lipid antigens.

Basic Information

Product Name	Tnpal-Galactocerebroside
CAS No.	118099-48-2
Molecular Formula	C55H100N4O16
Molecular Weight	1049.4 g/mol
Synonyms	Galactocerebroside, TNPAL derivative; N-[2,4,6-Trinitrophenyl]-6-aminocaproyl-galactosylceramide; TNPAL-GalCer; Trinitrophenylaminocaproyl Galactocerebroside; TNP-ε-aminocaproyl-galactocerebroside; Anti-galactocerebroside hapten; TNP-GalC; Galactocerebroside haptenated with TNP
EINECS	Contact for details

Quality Control

Our Tnpal-Galactocerebroside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. Each lot is characterized using advanced analytical techniques including HPLC, mass spectrometry, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere or desiccated conditions to maintain stability. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in chloroform/methanol mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.