Description

Ceftibuten Hydrate CAS NO 118081-37-1 is a semi-synthetic, third-generation cephalosporin antibiotic. This compound is valued for its broad-spectrum activity against Gram-negative bacteria and its stability against many β-lactamases. It is primarily used as a key pharmaceutical active ingredient in the formulation of oral antibiotic medications. The product is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring high-purity intermediates for antibiotic production.

Application

• Active Pharmaceutical Ingredient (API) in oral antibiotic formulations.
• Key intermediate in the synthesis of advanced cephalosporin derivatives.
• Reference standard for analytical and quality control laboratories.
• Research and development of new antibacterial agents in pharmaceutical R&D.
• Raw material for the preparation of clinical trial materials.
• Component in veterinary pharmaceutical preparations.

Basic Information

Product Name	Ceftibuten Hydrate
CAS No.	118081-37-1
Molecular Formula	C15H19N3O6S2 • xH2O
Molecular Weight	389.46 g/mol (anhydrous basis)
Synonyms	Ceftibuten; Ceftibuten Monohydrate; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-2-butenoylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Sch 39720; Cedax (Brand Name); Cefibuten; CEFTIB
EINECS	Contact for details

Quality Control

Our Ceftibuten Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support compliance with relevant pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	3.0% - 6.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Microbial Limit	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.