Description

1,2-Di-6,9-Hexacosadienoylphosphatidylcholine is a synthetic, high-purity phospholipid featuring defined diunsaturated fatty acid chains. This compound is a critical component for advanced research and formulation in lipid-based delivery systems, where membrane fluidity and structural integrity are paramount. It is primarily utilized by pharmaceutical researchers, cosmetic formulators, and biochemists developing liposomes, lipid nanoparticles (LNPs), and other sophisticated biomimetic membranes.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, fluidic bilayers in drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Biomembrane & Model Membrane Studies: Used in biophysical research to construct synthetic membranes that mimic specific cellular compartments or study lipid-protein interactions.
• Cosmetic & Dermal Delivery Systems: Incorporated into nanocarriers for topical applications to enhance the penetration and stability of active ingredients.
• Biochemical Reagent: Serves as a substrate or standard in enzymatic assays involving phospholipases or lipid metabolism studies.
• Diagnostic & Sensor Development: Utilized in the fabrication of lipid layers for biosensors and diagnostic platforms.

Basic Information

Product Name	1,2-Di-6,9-Hexacosadienoylphosphatidylcholine
CAS No.	117994-73-7
Molecular Formula	C66H122NO8P
Molecular Weight	1080.7 g/mol
Synonyms	PC(26:2(6,9)); 1,2-Di(6,9-hexacosadienoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine (26:2/26:2); D26:2 PC; Synthetic Phospholipid 26:2; 1,2-Dihexacosadienoylphosphatidylcholine; 1,2-Bis(6,9-hexacosadienoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Di-6,9-Hexacosadienoylphosphatidylcholine is manufactured under strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every lot to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 95% (Area %)
Purity (TLC)	Single spot
Fatty Acid Profile (GC)	Conforms to 26:2(6,9) structure
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.