Description

Tnpal-Sphingomyelin CAS NO 117985-56-5 is a high-purity, synthetic sphingomyelin analog, a critical component of cell membranes and lipid rafts. This compound is essential for advanced research and development in lipidomics, membrane biophysics, and the formulation of lipid-based drug delivery systems. It is particularly valuable for pharmaceutical, biotechnology, and academic laboratories requiring well-defined, high-quality lipid standards and excipients.

Application

• Lipidomics Research: Used as a critical standard and reference material for the identification and quantification of sphingolipids in complex biological samples via mass spectrometry.
• Membrane Biophysics Studies: Employed in model membrane systems (e.g., liposomes, supported lipid bilayers) to investigate membrane structure, fluidity, and protein-lipid interactions.
• Drug Delivery Formulations: Serves as a key excipient in the development of advanced liposomal and nanoparticle-based delivery vehicles for improved drug targeting and stability.
• Cell Biology & Signaling: Utilized to study the role of sphingomyelin and its metabolites in cellular processes such as apoptosis, proliferation, and signal transduction.
• Diagnostic Reagent Development: Acts as a component in the formulation of reagents and assays for clinical diagnostics related to lipid metabolism disorders.
• Cosmetic & Dermaceutical R&D: Incorporated in high-end skincare formulations for its role in skin barrier function and ceramide precursor activity.

Basic Information

Product Name	Tnpal-Sphingomyelin
CAS No.	117985-56-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-(Trinitrophenyl)-sphingomyelin; TNPAL-SM; TNPAL Sphingomyelin; Trinitrophenylamino lauryl sphingomyelin; 1-O-[2-(N-(2,4,6-Trinitrophenyl)amino)dodecanoyl]-2-N-acetylsphingosylphosphorylcholine; Fluorescent sphingomyelin analog; TNPAL labeled sphingomyelin
EINECS	Contact for details

Quality Control

Our Tnpal-Sphingomyelin is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for laboratory chemicals, and custom purity grades or specific analytical data can be provided upon request to meet your precise research or development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.