Description

N,N'-Bis(Iodoacetamide) is a versatile bifunctional alkylating agent and cross-linking reagent. This compound is critical for researchers and manufacturers requiring precise chemical modification of proteins, peptides, and other nucleophilic biomolecules. It is primarily utilized in life science research, pharmaceutical development, and the synthesis of advanced materials where the introduction of iodoacetamide functional groups is essential.

Application

• Bioconjugation and Protein Modification: Used to alkylate cysteine thiol groups in proteins and peptides for labeling, immobilization, or structural studies.
• Cross-linking Agent: Serves as a homobifunctional cross-linker to create intramolecular or intermolecular bridges in biomolecules.
• Enzyme Inhibition Studies: Acts as an active site-directed irreversible inhibitor for thiol-dependent enzymes.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex drug candidates and targeted therapeutic agents.
• Polymer and Material Science: Used as a monomer or modifier in the synthesis of functional polymers and smart materials.
• Proteomics Research: A key reagent for blocking reduced cysteine residues and preventing disulfide bond reformation in sample preparation.

Basic Information

Product Name	N,N'-Bis(Iodoacetamide)
CAS No.	117900-35-3
Molecular Formula	C6H8I2N2O2
Molecular Weight	393.95 g/mol
Synonyms	1,1'-(Azodicarbonyl)bis(2-iodoethanamine); N,N'-Diiodoacetylhydrazine; Bis(iodoacetamide); Iodoacetamide dimer; 2,2'-Iminodi(acetamide), 1,1'-diiodo-; N,N'-Bis(2-iodoacetyl)hydrazine; 1,1'-(Hydrazine-1,2-diyl)bis(2-iodoethan-1-one)
EINECS	Contact for details

Quality Control

Our N,N'-Bis(Iodoacetamide) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Keep the container tightly sealed under an inert atmosphere to minimize degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.