Description

Ac-Asp(Otbu)-Oh is a protected aspartic acid derivative, specifically an N-acetyl aspartic acid tert-butyl ester. This compound is a crucial building block in the synthesis of complex peptides and active pharmaceutical ingredients (APIs), offering precise control over molecular structure. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for advanced organic synthesis and drug development.

Application

• Peptide Synthesis: A key protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Serves as a critical building block in the production of therapeutic peptides and other bioactive molecules.
• Biochemical Research: Used in proteomics research and as a standard or reagent in enzymatic studies.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for drug discovery screening.
• Fine Chemical Production: Acts as a specialized intermediate in the synthesis of complex organic compounds.

Basic Information

Product Name	Ac-Asp(Otbu)-Oh
CAS No.	117833-18-8
Molecular Formula	C10H17NO5
Molecular Weight	231.25 g/mol
Synonyms	N-Acetyl-L-aspartic acid 4-tert-butyl ester; N-Acetyl-L-aspartic acid β-tert-butyl ester; Ac-L-Asp(OtBu)-OH; N-Acetylaspartic acid tert-butyl ester; (2S)-2-Acetamidobutanedioic acid 4-tert-butyl ester; N-Ac-Asp(OtBu)-OH; Ac-Asp(OtBu)-OH; Acetyl-L-aspartic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Ac-Asp(Otbu)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.