Description

17-Carboxy Desonide is a key pharmaceutical intermediate and metabolite of the corticosteroid Desonide. This compound is of significant value for research and development in the synthesis of novel anti-inflammatory agents and for analytical reference standards. It is primarily utilized by pharmaceutical R&D laboratories, analytical service providers, and manufacturers of active pharmaceutical ingredients (APIs) for quality control and metabolic studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and structural modification of corticosteroid-based drugs.
• Analytical Reference Standard: Used in HPLC, LC-MS, and other chromatographic methods for the quantification and purity assessment of Desonide and related compounds.
• Metabolite Studies: Essential for pharmacokinetic and drug metabolism research to understand the biological pathways of Desonide.
• Impurity Profiling: Serves as a certified impurity standard to ensure the quality and safety of Desonide API batches according to ICH guidelines.
• Research Chemical: Employed in biochemical and pharmacological research to investigate steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	17-Carboxy Desonide
CAS No.	117782-94-2
Molecular Formula	C24H32O7
Molecular Weight	432.51 g/mol
Synonyms	11β,21-Dihydroxy-16α,17α-isopropylidenedioxy-3,20-dioxopregna-1,4-diene-17β-carboxylic Acid; 17β-Carboxy Desonide; 17-Desonide Carboxylic Acid; 17-Carboxy-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione; 17-COOH Desonide; Desonide-17-carboxylic Acid; 17β-Carboxy-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 17-Carboxy Desonide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed results, ensuring traceability and compliance with research and pharmaceutical industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.