Description

n-Trifluoroacetylgalactosamine CAS NO 117766-36-6 is a chemically modified sugar derivative, specifically a trifluoroacetylated galactosamine, widely used as a key synthetic intermediate and biochemical tool. Its primary value lies in its role as a protected glycosyl donor or acceptor in the synthesis of complex oligosaccharides, glycoconjugates, and glycopeptides for advanced research. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, glycobiology research, and the production of diagnostic reagents.

Application

• Glycoconjugate Synthesis: A critical building block for the chemical and enzymatic synthesis of oligosaccharides, glycoproteins, and glycolipids.
• Pharmaceutical Intermediates: Used in the research and development of novel carbohydrate-based therapeutics, including antiviral and anticancer agents.
• Biochemical Probes: Serves as a precursor for labeled sugars (e.g., fluorescent or radioactive tags) used in metabolic pathway studies and cellular imaging.
• Glycochip and Array Fabrication: Employed to create functionalized sugars for immobilization on surfaces to study carbohydrate-protein interactions.
• Enzymology Studies: Acts as a substrate or inhibitor for glycosyltransferases, glycosidases, and other carbohydrate-processing enzymes.
• Diagnostic Reagent Development: Utilized in the manufacture of reagents for detecting specific antibodies or lectins in clinical and research settings.

Basic Information

Product Name	n-Trifluoroacetylgalactosamine
CAS No.	117766-36-6
Molecular Formula	C8H12F3NO6
Molecular Weight	275.18 g/mol
Synonyms	2-Acetamido-2-deoxy-1,3,4,6-tetra-O-trifluoroacetyl-α-D-galactopyranose; 2-Deoxy-2-(trifluoroacetamido)-1,3,4,6-tetra-O-trifluoroacetyl-D-galactopyranose; N-Trifluoroacetyl-D-galactosamine tetraacetate; Galactosamine, N-trifluoroacetyl-, tetraacetate; Per-O-trifluoroacetylated N-trifluoroacetylgalactosamine; D-Galactosamine, N-trifluoroacetyl-, 1,3,4,6-tetraacetate; TFA-GalNAc (tetra-O-TFA); TFAGalNAc(TFA)4
EINECS	Contact for details

Quality Control

Our n-Trifluoroacetylgalactosamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.