Description

n-Acylmannosamine 1-Dehydrogenase CAS NO 117698-08-5 is a specialized enzyme belonging to the oxidoreductase class, specifically catalyzing the oxidation of n-acylmannosamine derivatives. This compound matters as a critical biocatalyst in the synthesis of complex carbohydrates and sialic acid analogs, enabling precise and efficient biochemical transformations. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced glycobiology research, enzymatic synthesis, and the development of novel therapeutic agents and diagnostic tools.

Application

• Enzymatic Synthesis of Sialic Acid Derivatives: A key catalyst for the production of N-acetylneuraminic acid (Neu5Ac) and its analogs, which are vital components of glycoproteins and glycolipids.
• Glycobiology Research: Used as a tool enzyme to study metabolic pathways involving sialic acids and to probe cell surface glycan structures.
• Pharmaceutical Intermediate Production: Facilitates the biocatalytic manufacturing of intermediates for antiviral drugs, cancer therapeutics, and anti-inflammatory agents targeting glycan-mediated processes.
• Diagnostic Reagent Development: Employed in the formulation of enzymatic assay kits for the detection and quantification of specific carbohydrates or related enzyme activities.
• Biocatalyst Optimization Studies: Serves as a model enzyme for research into enzyme immobilization, stability enhancement, and reaction engineering in non-aqueous media.

Basic Information

Product Name	n-Acylmannosamine 1-Dehydrogenase
CAS No.	117698-08-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Acylmannosamine Dehydrogenase; N-Acyl-D-mannosamine Dehydrogenase; Acylmannosamine Dehydrogenase; EC 1.1.1.233; Mannosamine Dehydrogenase; Sialic Acid Synthesis Enzyme; Oxidoreductase, N-acylmannosamine; N-Acylmannosamine:NAD(P)+ 1-oxidoreductase
EINECS	Contact for details

Quality Control

Our n-Acylmannosamine 1-Dehydrogenase is produced and tested under stringent quality management protocols. Each batch undergoes rigorous analysis to ensure high specific activity, purity, and functional stability. Quality parameters are verified through methods including activity assays, SDS-PAGE for purity, and absence of contaminating protease activities. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to ensure full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. This material is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles to maintain optimal enzymatic activity. The product should be kept in its original container under the recommended conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	≥ [Value] U/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	Reported per batch
Stabilizers / Buffer	Reported per batch
Contaminating Protease Activity	Not detected

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.