Description

(Ala8,13,18)-Magainin II Amide is a synthetic, biologically active peptide analog derived from the natural antimicrobial peptide Magainin II. This modified sequence offers enhanced stability and specific activity profiles for research and development applications. It is primarily utilized by researchers in the fields of biochemistry, pharmaceutical development, and antimicrobial studies. The compound is identified by CAS No. 117665-48-2.

Application

• Antimicrobial Research: Investigation of mechanisms of action against bacteria, fungi, and other microorganisms.
• Drug Discovery: Serving as a lead compound or model for developing novel peptide-based therapeutics.
• Biophysical Studies: Analysis of peptide-lipid membrane interactions and structure-activity relationships (SAR).
• Biochemical Reagent: Use as a high-purity standard or active component in experimental assays.
• Academic & Institutional Research: Fundamental research in immunology, peptide chemistry, and molecular biology.

Basic Information

Product Name	(Ala8,13,18)-Magainin II Amide
CAS No.	117665-48-2
Molecular Formula	C108H168N30O20
Molecular Weight	2294.7 g/mol
Synonyms	Magainin 2 (Ala8,13,18) amide; (Ala8,13,18)-Magainin 2 amide; Antimicrobial peptide analog; GIGKFLHSAKKFGKAFVGEIMNS amide (Ala-substituted); Pexiganan precursor analog; MSI-238 analog
EINECS	Contact for details

Quality Control

Our (Ala8,13,18)-Magainin II Amide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets rigorous research-grade specifications. A Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.