Description

Remoxipride Hydrochloride Monohydrate is a high-purity pharmaceutical intermediate and reference standard. This compound is critical for research and development in neuropharmacology, serving as a selective dopamine D2 receptor antagonist. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in the development of central nervous system (CNS) therapeutics and quality control processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced neuroleptic drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) testing in pharmaceutical manufacturing.
• Biochemical Research: A vital tool for studying dopamine receptor subtypes, their function, and signal transduction pathways in vitro.
• Preclinical Studies: Employed in animal model research to investigate the pharmacology and potential therapeutic effects of D2 antagonism.
• Impurity Profiling: Serves as a certified reference material for identifying and quantifying related substances in active pharmaceutical ingredient (API) batches.
• Metabolite Synthesis: Used as a starting material for the preparation of potential human metabolites for safety and toxicology studies.

Basic Information

Product Name	Remoxipride Hydrochloride Monohydrate
CAS No.	117591-79-4
Molecular Formula	C16H23BrN2O3 • HCl • H2O
Molecular Weight	419.74 g/mol (Monohydrate)
Synonyms	(-)-(S)-3-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxybenzamide Hydrochloride Monohydrate; Remoxipride HCl Monohydrate; FLA 731; Roxiam; Remoxiprid Hydrochloride Monohydrate; (S)-(-)-3-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxybenzamide Hydrochloride Monohydrate
EINECS	Contact for details

Quality Control

Our Remoxipride Hydrochloride Monohydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	3.5% - 5.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.