Description

3-Bromo-4-Methoxybenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and methoxy substituents, makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionality.
• Liquid Crystal Materials: Serves as a precursor for mesogenic compounds used in display technologies (LCDs).
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable building block for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	3-Bromo-4-Methoxybenzonitrile
CAS No.	117572-79-9
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	4-Methoxy-3-bromobenzonitrile; 3-Bromo-4-methoxybenzenecarbonitrile; 3-Bromo-p-anisonitrile; Benzonitrile, 3-bromo-4-methoxy-; 3-Bromo-4-methoxy phenyl cyanide; 3-Br-4-MeO-BnCN
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.