Description

1-Fluoro-2-Methoxymethoxy-Benzene is a versatile fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and a protected hydroxyl equivalent, makes it a valuable precursor for constructing complex molecules where precise electronic and steric control is required. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms into complex molecular scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for creating biaryl and other complex aromatic systems.
• Protecting Group Chemistry: The methoxymethoxy (MOM) group can act as a protective group for phenols in multi-step synthetic sequences.
• Material Science Research: Employed in the synthesis of novel polymers and specialty chemicals with tailored properties.

Basic Information

Product Name	1-Fluoro-2-Methoxymethoxy-Benzene
CAS No.	117570-31-7
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	2-Fluoro-1-Methoxymethoxybenzene; 1-Fluoro-2-(methoxymethoxy)benzene; o-Fluoroanisole MOM ether; Benzene, 1-fluoro-2-(methoxymethoxy)-; 2-(Methoxymethoxy)fluorobenzene; Fluorobenzene, 2-(methoxymethoxy)-; MOM ether of 2-Fluorophenol
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2-Methoxymethoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.