Description

Rac Viloxazine-D5 Hydrochloride is a deuterated isotopologue of the active pharmaceutical ingredient viloxazine, a selective norepinephrine reuptake inhibitor. This high-purity reference standard is critical for ensuring the accuracy and reliability of analytical methods in pharmaceutical research and development. It is primarily utilized by analytical chemists and quality control laboratories in the pharmaceutical and contract research organization (CRO) sectors for applications such as method development, validation, and bioanalytical studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary or secondary standard for the quantitative analysis of viloxazine in drug substances and products.
• Metabolite Studies: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the precise quantification of viloxazine and its metabolites in biological matrices (e.g., plasma, serum).
• Method Development & Validation: Essential for developing and validating robust analytical methods (HPLC, UPLC) to meet ICH and FDA guidelines.
• Doping Control & Forensic Analysis: Employed in sports anti-doping and forensic toxicology laboratories for the definitive identification and measurement of viloxazine.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Research: Facilitates accurate drug level monitoring in clinical and non-clinical studies to understand absorption, distribution, metabolism, and excretion.
• Quality Control (QC) Testing: Used in-house by pharmaceutical manufacturers to ensure batch-to-batch consistency and compliance with regulatory specifications.

Basic Information

Product Name	Rac Viloxazine-D5 Hydrochloride
CAS No.	117320-32-8
Molecular Formula	C15H18D5ClN2O2
Molecular Weight	295.83 g/mol
Synonyms	2-[(2-Ethoxyphenoxy)methyl]morpholine-2,2,3,3,6-d5 Hydrochloride; (±)-Viloxazine-d5 HCl; DL-Viloxazine-d5 Hydrochloride; Vivalan-d5 Hydrochloride; Vicilan-d5 HCl; ICI 58,834-d5; CATABRAN-d5; CVL 491-d5
EINECS	Contact for details

Quality Control

Our Rac Viloxazine-D5 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm structural identity, isotopic purity (D5), and chemical purity. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against predefined specifications. Our quality commitment ensures the material is suitable for use as a reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.