Description

3-(4-Methoxy-Phenyl)-3-(2,2,2-Trifluoro-Acetylamino)-Propionic Acid is a specialized fluorinated organic compound that serves as a critical intermediate in advanced synthetic chemistry. Its unique structure, featuring a trifluoroacetyl-protected amino group on a propionic acid backbone, makes it a valuable building block for constructing complex molecules with enhanced properties. This high-purity intermediate is essential for research and development teams in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the introduction of fluorine atoms can significantly enhance biological activity and environmental persistence.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules, peptides, and peptidomimetics due to its reactive carboxylic acid and protected amine functionalities.
• Material Science Research: Acts as a precursor for specialty polymers and advanced materials that incorporate fluorinated groups for specific thermal, chemical, or surface properties.
• Fluorine Chemistry Studies: Serves as a standard or reagent in methodological development within fluorine chemistry, helping to explore new synthetic pathways involving trifluoroacetyl groups.

Basic Information

Product Name	3-(4-Methoxy-Phenyl)-3-(2,2,2-Trifluoro-Acetylamino)-Propionic Acid
CAS No.	117291-24-4
Molecular Formula	C12H12F3NO4
Molecular Weight	291.22 g/mol
Synonyms	3-(4-Methoxyphenyl)-3-[(2,2,2-trifluoroacetyl)amino]propanoic acid; 3-(4-Methoxy-Phenyl)-3-(2,2,2-Trifluoroacetamido)-Propionic Acid; 3-(4-Methoxyphenyl)-3-(trifluoroacetamido)propanoic acid; N-(3-Carboxy-3-(4-methoxyphenyl)propyl)-2,2,2-trifluoroacetamide; 117291-24-4; TFAPA derivative; Trifluoroacetyl amino acid derivative
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methoxy-Phenyl)-3-(2,2,2-Trifluoro-Acetylamino)-Propionic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, and we support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.