Description

2-(2,2-Difluoro-Cyclopropyl)-Ethanol is a versatile fluorinated building block characterized by its unique difluorocyclopropane ring fused with an ethanol side chain. This compound is of significant value in advanced organic synthesis, particularly for introducing fluorinated motifs that can dramatically alter the physicochemical and biological properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated analogs of drug candidates to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorine substitution is critical for activity and environmental profile.
• Material Science Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers and coatings with tailored surface properties.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying cyclopropane ring-opening reactions and fluorination methodologies in academic and industrial R&D settings.

Basic Information

Product Name	2-(2,2-Difluoro-Cyclopropyl)-Ethanol
CAS No.	117284-59-0
Molecular Formula	C5H8F2O
Molecular Weight	122.11 g/mol
Synonyms	2-(2,2-Difluorocyclopropyl)ethanol; 2-(2,2-Difluorocyclopropyl)ethan-1-ol; 2,2-Difluorocyclopropanemethanol (homolog); Ethanol, 2-(2,2-difluorocyclopropyl)-; 117284-59-0; 2-(2,2-Difluoro-cyclopropyl)-ethanol
EINECS	Contact for details

Quality Control

Our 2-(2,2-Difluoro-Cyclopropyl)-Ethanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for manufacturing where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.