Description

2-Pyrrolidinecarbothioamide,(R)-(9Ci) is a high-purity chiral thiourea derivative, specifically the (R)-enantiomer, which serves as a critical building block and chiral auxiliary in advanced organic synthesis. Its value lies in its ability to impart stereoselectivity and act as a ligand or catalyst in asymmetric transformations, enabling the production of enantiomerically pure compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who are developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Catalysis: Employed as a chiral ligand or organocatalyst in enantioselective synthesis, including Michael additions, aldol reactions, and hydrogenations.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators to enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Serves as a precursor for the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and for exploring new reaction pathways in process chemistry.

Basic Information

Product Name	2-Pyrrolidinecarbothioamide,(R)-(9Ci)
CAS No.	117175-43-6
Molecular Formula	C5H10N2S
Molecular Weight	130.21 g/mol
Synonyms	(R)-2-Pyrrolidinecarbothioamide; (R)-Pyrrolidine-2-carbothioamide; (R)-Proline thioamide; (R)-2-Aminocarbonylthiopyrrolidine; (R)-Thioproline amide; (R)-2-Carbamothioylpyrrolidine; (9CI) designation for CAS indexing.
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarbothioamide,(R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.